As I have related before, there are other symptoms of Essential Tremor (ET) beyond the shaking of hands, head and voice. It is an area that requires much more research. In HopeNET’s groups, the issue of migraines has come up a number of times. In the meantime, my daughter who supposedly does not have ET has suffered badly from migraines.\u00a0\u00a0As my ET is hereditary, she & I\u00a0had discussed the connection between ET & migraines a number of times. Then she found this article doing an internet search and forwarded it to me. It substantiates the connection between ET and migraines.<\/p>\n
This raises another important issue of\u00a0children who supposedly don’t have ET. Do all the children inherit ET to some degree? This question needs to be answered, and if so, what is the effect?<\/p>\n
I welcome any comments you have.<\/p>\n
Peter Muller
\nExecutive Director
\nHopeNET<\/p>\n
Yueqing Hu, Wenjing Tang, Ruozhuo Liu, Zhao Dong, Xiaoyan Chen, Meiyan Pan and Shengyuan Yu<\/p>\n
Background:<\/strong> The existence of an association between migraine and essential tremor has long been controversial. The prevalence of migraine in essential tremor patients was surveyed to explore the association between the two diseases.<\/p>\n Methods:<\/strong> A case-control clinical study was conducted to investigate the prevalence of migraine in 150 consecutive Results:<\/strong> The prevalence of lifetime migraine in essential tremor patients was significantly higher than that in controls (22.0% vs. 12.7%; p\u00bc0.035; odds ratio\u00bc1.95; 95% confidence interval\u00bc1.05\u20133.60). No significant difference was found in the migraine features between the essential tremor and control groups and most tremor characteristics were no different in essential tremor patients with and without migraine. A higher male prevalence of essential tremor patients without migraine was observed. Moreover, 44 of 46 (95.7%) essential tremor patients had the dopamine receptor D3 Ser9Gly variant, but no significant difference was found in the frequencies of the variant between essential tremor patients with and without migraine (87.5% vs. 100.0%; p\u00bc0.22).<\/p>\n Conclusion:<\/strong> Our data suggest that essential tremor patients have a higher risk of lifetime migraine than do controls and the dopamine receptor D3 Ser9Gly variant may be lower in essential tremor with migraine than the general essential tremor patients.<\/p>\n Keywords<\/strong> Date received: 5 January 2014; accepted: 12 March 2014<\/p>\n <\/p>\n Full Article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
\nessential tremor patients and in 150 matched controls without tremor. Detailed information about essential tremor
\nand migraine was obtained using a structured questionnaire at a face-to-face interview. Moreover, a functional variant of the dopamine receptor D3 gene (Ser9Gly, rs6280) was studied in 46 essential tremor patients with and without migraine using direct sequencing analysis.<\/p>\n
\nEssential tremor, migraine, dopamine receptor D3 gene, risk factor<\/p>\n